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NIFDC Notice on the Proposed Update of Prohibited Cosmetic Ingredient List and Seven Test Methods

Prohibited Cosmetic Ingredient List

On June 12, 2023, China's National Institutes for Food and Drug Control (NIFDC) issued a notice on the proposed update of the prohibited cosmetic ingredient list and seven test methods, and opened for public consultation.

If you have any comments or suggestions, please fill in and send the feedback form (Annex 9 of the original website) to before July 15, 2023.

Five new prohibited cosmetic ingredients


​Chinese Name

​English Name



​Bimatoprost (CAS No. 155206-00-1)



​Latanoprost (CAS No. 130209-82-4)



​Tafluprost (CAS No.209860-87-7)



​Tafluprost ethyl amide,(5Z)-7-{(1R,2R,3R,5S)-2-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl}-N-ethyl-5-heptenamide (CAS No. 1185851-52-8)



​Travoprost (CAS No. 157283-68-6)

Seven test methods

1. 28-Day Inhalation Toxicity Study

2. 90-Day Inhalation Toxicity Study

3. Extended one-generation reproductive toxicity study

4. Two-generation reproductive toxicity

5. Skin Absorption-In Vivo Method

6. Acute Inhalation Toxicity Acute Toxic Class Method

7. U937 cell line activation Test

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