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NMPA Announces! Five in Vitro Test Methods are Officially Included in Cosmetics Safety Regulations

  • Lucia
  • Sep 1
  • 1 min read
The "Bovine Corneal Turbidity and Permeability Test Method" and five other in vitro test methods were officially released.

Five methods drafted by the NMPA, including the "Bovine Corneal Turbidity and Permeability Test Method," the "In Vitro Skin Allergy Kinetic Direct Peptide Reaction Test Method," the "In Vitro Skin Absorption Test Method," the "Immunotoxicity Test Method," and the "Oral Mucosal Irritation Test Method," have been reviewed and approved and are now published and incorporated into the corresponding sections of the "Cosmetics Safety Technical Specifications (2015 Edition)" (see Appendix).


These five methods are all new and will be implemented starting March 1, 2026. Prior to implementation, the use of these methods in cosmetics registration and filing inspections is encouraged.


Annex:

1. Summary Table of the Five Standard Development Items for the "Cosmetics Safety Technical Specifications (2015 Edition)"

2. Bovine Corneal Turbidity and Permeability Test Methods

3. In Vitro Skin Allergy Kinetic Direct Peptide Reaction Test Methods

4. In Vitro Skin Absorption Test Methods

5. Immunotoxicity Test Methods

6. Oral Mucosa Irritation Test Methods



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